FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of ...

A mechanism underlying neutrophil reprogramming in brain cancers has been uncovered, illuminating potential therapeutic targets to stop their pro-cancer effect. Tumor-infiltrating neutrophils are ...

Aging is a complex process that has long puzzled scientists. A recent study published in Engineering proposes a new theory called Pro-Aging Metabolic Reprogramming (PAMRP), which could change our ...

For decades, scientists have known that what harms the body often harms the brain. Conditions such as obesity, high blood pressure and insulin resistance strain the body's vascular and metabolic ...

Novel protein biomarkers for early detection of pancreatic ductal adenocarcinoma using longitudinal serum protein measurements and machine learning. This is an ASCO Meeting Abstract from the 2025 ASCO ...

Taking care of oneself requires a multi-faceted approach: brain, heart, and metabolic health. What research in 2024 has shown us is that improving our health in these areas comes down to three main ...

One reason that chronic pain, mental or physical is consistently solvable is the brain’s property of neuroplasticity. Your brain physically constantly changes based on the nature of the sensory input.

Metabolic reprogramming in fibrotic lung diseases involves key metabolites like lactate, succinate, and 2-hydroxyglutarate, driving inflammation and fibroblast activation. Lactate accumulation ...