Global understanding of complement has shifted and developed since the 21st century: from our idea of a blood-based antibiotic system to a global regulator of immunity and tissue homeostasis. Recent ...

Immunotherapy is a type of cancer treatment that uses the body's own immune system to fight tumor cells. While much focus has been on engaging T-cells for fighting cancer, less attention has been ...

Figure 1: Mannose-binding lectin (blue strands) can bind to sites on the SARS-Cov-2 spike protein on the cell membrane. One of the most striking features of the SARS-CoV-2 pandemic is that across all ...

In a recent study published in The New England Journal of Medicine, researchers reviewed selected acute-phase proteins concerning their production, structure, and function. The advent of severe acute ...

Expert Rev Clin Immunol. 2008;4(3):379-390. Since there are no genetic deficiencies of CRP in man, animal models have been used to study the role of CRP in inflammatory disease. Two methods have been ...

A new generation of cancer therapies has emerged over the past few decades, including checkpoint inhibitors and chimeric antigen receptor (CAR) T-cell therapies that modify or directly use T-cells to ...

A discovery could offer new methods for treating HIV, while uncovering the innate immune system's role in other diseases. Human immunodeficiency virus 1, more commonly known as HIV-1, is known for its ...