Nonspecific histone deacetylase (HDAC) inhibition has been shown to facilitate the extinction of drug-seeking behavior in a manner resistant to reinstatement. A key open question is which specific ...

Astronomers from the Aryabhatta Research Institute of Observational Sciences (ARIES) in India and elsewhere have conducted a ...

Researchers have shown that enzymes working at the synapses of medium spiny neurons (MSN) are associated with drug-seeking and extinction behaviors. These novel molecules, they say, may become ...

Until recently, I assumed that the term “extinction burst” referred to the impact of the comet, asteroid or other catastrophic space rock that wiped out the dinosaurs. Turns out the expression ...

Addiction, or substance use disorder (SUD), is a complex neurological condition that includes drug-seeking behavior among other cognitive, emotional and behavioral features. Synaptic plasticity, or ...

IntroductionAnxiety and anxiety-influenced disorders are sexually dimorphic with women being disproportionately affected compared to men. Given the increased prevalence in women and the documented ...