The William H. Foege Genome Sciences Building at the University of Washington School of Medicine in Seattle contains laboratories, sequencers, computational facilities, and other resources for ...

Mutation rate, as a biological process, denotes the frequency at which heritable changes in nucleotide sequence arise per genome, gene, or nucleotide per cell division or per unit time, driven by ...

Retrospective study of fluoropyrimidine chemotherapy dosing and toxicity in patients with screen-detected deleterious DPYD gene variants. Real-world treatment patterns, healthcare resource utilization ...

Using sequencing instruments from multiple vendors, scientists from the University of Utah Health, the University of Washington, PacBio, and elsewhere have developed what they claim is the most ...

This mutation is directly linked to transcriptional activity: the more a promoter is active, the more frequently mutations ...

Scientists have discovered a key 'survival gene' that prevents strains of tuberculosis (TB) from mutating into drug-resistant 'superbugs'. In a joint study, published today, Friday January 27th 2017, ...

Scientists have systematically analyzed somatic mutations in stomach lining tissue to unpick mutational processes, some of which can lead to cancer. The team also uncovered hints of a potential new ...