A research team led by Purdue University’s W. Andy Tao has discovered of a new type of protein modification related to cellular mutation that impairs a crucial enzyme’s ability to help drive energy ...

Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...

Protein palmitoylation and lipid modifications are essential post‐translational processes that regulate protein localisation, stability and function by the covalent attachment of fatty acid chains.

Virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how our bodies detect and respond to viruses and viral replication. The publication explains ...

Neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, present a significant health challenge, affecting over 50 million people globally. One common feature of these diseases is the ...

Protein AMPylation represents a specialised post‐translational modification (PTM) in which an adenosine monophosphate (AMP) moiety is covalently attached to specific amino acid residues on target ...

Exploring the post-translational modifications of a key protein in Parkinson's disease, researchers uncover potential pathways for future therapies in neurodegenerative diseases in general.

Scientists have pinpointed the enzyme YcaO as responsible for a rare ribosomal protein modification in several pathogenic bacteria, a process absent in humans. The finding could open new avenues for ...

A research team led by Purdue University’s W. Andy Tao (front) has discovered of a new type of protein modification related to cellular mutation that impairs a crucial enzyme’s ability to help drive ...

A research team led by Prof. Wang Yi and Wei Haiming from the University of Science and Technology of China (USTC), in collaboration with Prof. Ding Chen's team from Human Phenome Institute at Fudan ...