In clinical trials with sequential patient entry, fixed sample size designs are unjustified on ethical grounds and sequential designs are often impracticable. One solution is a group sequential design ...

Stay up to date on the latest science with Brush Up Summaries. What Is Single Cell Sequencing? Single cell sequencing is a collection of methods that researchers use to isolate and analyze sequence ...

PLAMseq utilizes a rapid biotinylation enzyme called TurboID, which tags nearby proteins, enabling the genomic loci and ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

Whole genome analysis plays a critical role in the development of life-saving diagnostics, therapeutics, and vaccines, with growing interest in noncoding regions and Whole genome analysis plays a ...

This image illustrates the typical steps in next-generation sequencing (excluding single-molecule sequencing methods). The process begins with isolating genomic DNA (a) and breaking it into short ...