CLL primary cells and the CLL cell line HG3 were cultured in RPMI-1640 containing 10% fetal bovine serum, 50 U/ml penicillin, 50 mg/ml streptomycin and 2 mM L-glutamine (complete medium; Invitrogen ...

The expert in complement therapeutics development, Creative Biolabs, keys the importance of complement function and activity tests in complement defect screening and drug development. The complement ...

ARO-C3 treatment led to deep and sustained reductions in alternative pathway complement activity and proteinuria. ARO-C3, an investigational RNA interference-based therapy targeting hepatic expression ...