Non-coding DNA variants contribute to acute lymphoblastic leukemia (ALL) chemotherapy resistance. St. Jude Children's Research Hospital scientists have identified specific DNA variants in the ...

DNA coding theory bridges the disciplines of mathematics, computer science and molecular biology by applying advanced algebraic and combinatorial techniques to the design of nucleotide sequences. This ...

(L to R) Co-first author Jackson Mobley, PhD, corresponding author Daniel Savic, PhD, and co-first author Kashi Raj Bhattarai, PhD, all of the St. Jude Department of Pharmacy and Pharmaceutical ...

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions of the cell, the rest of the genome cannot be ignored. However, for decades ...

Researchers have discovered a 'genomic tug of war' in animal studies that could influence how well certain patients -- or certain cancers -- respond to decitabine, a drug used to treat myelodysplastic ...

Researchers have revealed that so-called ‘junk DNA’ contains powerful switches that help control brain cells linked to Alzheimer’s disease. When people picture DNA, they often imagine a set of genes ...

When AlphaFold solved the protein-folding problem in 2020, it showed that artificial intelligence could crack one of biology’s deepest mysteries: how a string of amino acids folds itself into a ...

最值得关注的是，该突变发生在非编码 DNA 区域 —— 人类 98% 的 DNA 不编码基因，曾被视为 “垃圾 DNA”，如今证实其像软件一样调控基因激活与蛋白质合成。此次突变的是名为 Enh13 的非编码调控元件，它是转录因子的 ...

Forbes contributors publish independent expert analyses and insights. Recent breakthroughs in genetics research may have uncovered new genes underlying common psychiatric disorders. Schizophrenia and ...