Researchers in Finland have combined virtual drug screening with machine learning (ML) – carried out on supercomputers – to dramatically shorten the time taken to identify candidate molecules. Virtual ...

Hellgren et al. develop AEGIS, a transcriptomics-based tool that quantifies apoptosis-linked gene signatures to assess drug-induced liver injury risk across doses, in vitro models, species, and ...

Phenotypic screening is a strategy for the identification of molecules with particular biological effects in cell-based assays or animal models. For example, it can involve screening large libraries ...