Introduction: Carbapenemase-producing bacteria undermine the efficacy of carbapenems, a class of last-resort antibiotics used primarily to treat infections caused by multidrug-resistant Gram-negative ...

Evaluation of scCNV inference methods using a clinical small cell lung cancer (SCLC) dataset. (A) Sensitivity and specificity of the four scCNV inference methods applied to primary and relapse SCLC ...

I've used Savana to detect both CNVs and SVs in a tumor-normal pair with 40x coverage (ONT). But when looking at the SV vcf, I find no matching deletion/duplication as the CNV algorithm. For SV, it ...

Background: Developmental delay (DD) and intellectual disability (ID) are prevalent in children and often have genetic causes, particularly copy number variations (CNVs). Chromosomal microarray ...

*These authors contributed equally to the preparation of this manuscript. Cell-based technologies for printing protein microarrays are faced with poor protein expression, protein insolubility, ...

Oxford Gene Technology has announced the launch of its newly updated NGS SureSeq™ CLL + CNV V3 Panel. This new panel was designed to offer users more comprehensive variant detection to improve ...

Join us to explore the latest advancements in pharmacogenomic (PGx) analysis with our newly launched Infinium microarrays and DRAGEN Array software. The Infinium Global Clinical Research Array with ...

Most CNV detection methods are specifically developed for diploid genomes without specific consideration of effects on haploid genomes. Single-cell or low-input sequencing data generally displays ...

Two researchers independently conducted study selection, extracted data, and assessed the risk of bias using an adapted Quality Assessment of Studies of Diagnostic Accuracy-Revised tool. We used both ...