This review synthesizes clinical, genetic, and mechanistic evidence showing that suPAR and related uPAR fragments are ...

Medical University of South Carolina scientists have uncovered a link between the innate immune system and cognitive problems ...

Recent advances in the understanding of immune-mediated neurological disorders have led to a paradigm shift toward pathophysiology-directed therapies. Central to this progress is a deeper appreciation ...

Windows Activation helps verify that your copy of Windows is genuine and hasn’t been used on more devices than the Microsoft Software License Terms allow. 1] Are you using the right product key? Make ...

ARO-C3 treatment led to deep and sustained reductions in alternative pathway complement activity and proteinuria. ARO-C3, an investigational RNA interference-based therapy targeting hepatic expression ...

Scientists at the University of Pennsylvania have uncovered the mathematical rules that govern one of the body’s oldest and most important immune system defenses, the complement system, according to ...

Please provide your email address to receive an email when new articles are posted on . A protein known as granzyme K was recently shown to be a driver of inflammation by activating the complement ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The complement system plays crucial roles in ...

Researchers identify a new player in human immunity that can go rogue and turn the immune system against the body’s own tissues. The protein, called granzyme K, whose role until now was unclear, ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The complement system and neutrophils ...

Findings suggest that the complement system plays a role in the onset of acute kidney injury in critically ill patients. Urinary Ba, a fragment of complement factor B, may be a biomarker and mediator ...

Dianthus achieved its NASDAQ listing last year via a merger with Magenta Therapeutics. The company is focused on development of a single drug candidate, DNTH-103, which targets the complement system, ...