RNA sequencing (RNA-Seq) is a high-throughput sequencing approach that enables comprehensive quantification of transcriptomes at a genome-wide scale. As a result, RNA-Seq has become a routine ...

RNA sequencing (RNA-seq) is a powerful tool in diagnosing Mendelian disorders, but the optimized sequencing depth for this technology has not yet been determined. In a new study published in the ...

Total RNA from 716 hand-isolated germinal vesicles from oocytes of a mature Xenopus tropicalis frog Data were extracted from the CEL files, RMA normalized across all samples and converted to Log2 ...

Total RNA from 1,008 hand-isolated, demembranated germinal vesicles from oocytes of a mature Xenopus tropicalis frog Data were extracted from the CEL files, RMA normalized across all samples and ...

What biological questions can single-molecule RNA sequencing help address that traditional methods cannot? How can these technologies be applied in your area of research, and what limitations might ...

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Abstract: It is notorious that single-cell RNA sequencing (scRNA-seq) data contain a significant number of missing values due to technical variability. The issue of missing values presents a major ...

RNA sequencing has emerged as a powerful supplement to DNA sequencing for Mendelian disease diagnosis, but clinical translation of diagnostic RNA-seq has not been widely achieved. Researchers at ...

An individual’s genome is identifiable. But datasets of RNA sequences from single cells are like a blurry photocopy of the genome. The sequence numbers are small, the data are noisy, and the sequences ...