This is the first time we have connected a cranium to Denisovans,” said evolutionary geneticist Qiaomei Fu, and in this way, ...

A molecular model showing three of the main epigenetic modifications of DNA (orange) and histones (dark blue) [JUAN GAERTNER/Science Photo Library/Getty Images] Post-translational modifications (PTMs) ...

Abstract: Lysine post-translational modification (PTM) is involved in almost all cellular activities, and plays a critical role in protein structure and function. In the past decades, a variety of ...

Abstract: O-linked glycosylation is a complex form of posttranslational modification in human proteins that plays a crucial regulatory role in a wide range of cell types. It is intimately involved in ...

The tumor suppressor p53 is activated by a range of cellular stresses including DNA damage, oncogenic signals, and nutrient deprivation. Upon activation, p53 transcriptionally upregulates an extensive ...

Respiratory infections, pink eye, or an upset stomach may seem like unrelated, mild inconveniences, but all of these ailments share one root cause: adenovirus infection. Many of us will encounter some ...

Recent work in The EMBO Journal describes a new hybrid post-translational modification of proteins, composed of a poly-ubiquitin chain that is attached to a target protein via a mono-ADP-ribose (MAR) ...

ABSTRACT: Protein-based therapeutics (PPTs) are drugs used to treat a variety of different conditions in the human body by alleviating enzymatic deficiencies, augmenting other proteins and drugs, ...

Protein-based therapeutics (PPTs) are drugs used to treat a variety of different conditions in the human body by alleviating enzymatic deficiencies, augmenting other proteins and drugs, modulating ...