Diabetic kidney disease affects a growing proportion of people with diabetes and remains the leading cause of end-stage renal ...

Diabetic kidney disease is a leading cause of kidney failure worldwide, yet current treatments often slow progression sustained improvement in kidney ...

This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers ...

New findings could aid future development of more efficient therapeutic strategies in the context of regenerative medicine and aging.

Metabolic reprogramming in the tumor microenvironment shapes immune function and therapy resistance, offering insights into ...

New research has mapped the cell types that specialise to form reproductive organs in both sexes, identifying key genes and signals that drive this ...

New research has mapped the cell types that specialize to form reproductive organs in both sexes, identifying key genes and signals that drive this process. The findings offer important insights into ...

The preprint is available here. DeepSpot2Cell predicts virtual single-cell spatial transcriptomics as follows: (1) During training, the model takes as input (i) the cropped cell tile defined by the ...

Single-cell RNA sequencing (scRNA-seq) has profoundly reshaped our understanding of cellular diversity and functionality; however, accurate cell-type annotation is required for biological ...

A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...