Age-related intervertebral disc (IVD) pathologies are a major driver of chronic low back pain and disability. Long framed as ...

Abstract: Spatial transcriptomics is an emerging technology that allows for analysis of cellular and molecular heterogeneity at spatial resolution. The accurate identification of pathological regions ...

The diagnostic armamentarium for solid tumors is evolving rapidly, redefining how we detect, stage, stratify, monitor, and ultimately treat cancer. This ...

This article explores how single-cell multiomics and spatial transcriptomics are illuminating early pregnancy, uncovering ...

Scientists at Duke-NUS Medical School have developed two powerful computational tools that could transform how researchers ...

Spatially resolved transcriptomics (SRT) simultaneously captures spatial coordinates, pathological features, and transcriptional profiles of cells within intact tissues, offering unprecedented ...

Abstract: Spatial transcriptomics (ST) is a novel technique that simultaneously captures pathological images and gene expression profiling with spatial coordinates. Since ST is closely related to ...

The preprint is available here. DeepSpot2Cell predicts virtual single-cell spatial transcriptomics as follows: (1) During training, the model takes as input (i) the cropped cell tile defined by the ...

Background Intraductal papillary mucinous neoplasms (IPMNs) are precursor lesions of pancreatic cancer with highly variable malignant potential. Current understanding of their biology remains ...