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Winters' formula, named after Dr. R.W. Winters, is a medical formula used to assess respiratory compensation when analyzing acid-base disorders, particularly in cases of metabolic acidosis. It helps clinicians evaluate whether the respiratory system is responding adequately to the underlying acid-base disturbance. The formula is “PCO2 = (1.5 × HCO3-) 8 ± 2” . Winters' formula provides an expected or calculated value for the patient's PCO2 based solely on the bicarbonate concentration. . Clinicia
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